1) There is a big bowl at the front desk where everyone drops their keys. You are told to leave your valuables in the car. It's not the most secure system, but my coworkers have done this for years with no stories of stolen vehicles or valuables. Their facility is on the edge of town on a private lot so anyone going there to steal items would be noticed. You could also carry your valuables in a water proof pouch, but make sure it's a high quality pouch with a strap or your stuff could get water damaged or lost in the river. 2) There is a restroom at their main facility and port a potties at the launch site and landing site. I also am sure there are port a potties at the lunch stop during the full day trip. Bottom line is, you should use the restroom before departing their main facility. 3) I assume that if you told the guide you need to use the bathroom they could land at one of the campsites along the route with port a potties. 3) There are about 3 chances during the trip to jump in the water and float alongside the boat. I suppose you could use that opportunity to go to the bathroom in case of an emergency.